منابع مشابه
Macrophage Phagocytosis of Aging Neutrophils in Inflammation
Mechanisms governing the normal resolution processes of inflammation are poorly understood, yet their elucidation may lead to a greater understanding of the pathogenesis of chronic inflammation. The removal of neutrophils and their potentially histotoxic contents is one prerequisite of resolution. Engulfment by macrophages is an important disposal route, and changes in the senescent neutrophil ...
متن کاملApoptosis (programmed cell death) and functional changes in aging neutrophils. Modulation by inflammatory mediators.
6S 33rd Annual Thomas L Petty Aspen Lung Conference anism. Tox Appi Pharm 1979; 51:475-87 37 Haslett C, Hanson PM. Resolution of inflammation. In: Clark RAF, Hanson PM, eds. The Molecular and Cellular Biology of Wound Repair, Chapter 7. New York: Plenum Publishing Corporation, 1988:185-211 38 Leibovich SJ, Ross B. The role of the macrophage in wound repair. Am J Pathol 1975; 78:71-91 39 Leslie ...
متن کاملKinetic evaluation of the pool sizes and proliferative response of neutrophils in bacterially challenged aging mice.
Clinical observations during infection suggest that in aged patients, the kinetic or proliferative responses of neutrophils to infection may be deranged. To test this hypothesis, the neutrophil responses of 6-month-old and 30-month-old mice were compared. After intrapulmonary injection of Escherichia coli, young mice exhibited neutrophilia and diminution of the neutrophil storage pool (NSP) by ...
متن کاملe dynamics of morphological changes during in vitro aging of bovine virgin mammary gland neutrophils
e present study was an in vitro analysis of the dynamics of bovine mammary gland neutrophil apoptosis based on the detection of morphological changes. e neutrophils were isolated from mammary glands of five virgin heifers. e mammary glands were lavaged, the suspensions were then bacteriologically examined, and total and differential cell counts were made. e cells were cultivated in vitro fo...
متن کاملImmunological effects of Teucrium polium on neutrophils
Teucrium polium, a medicinal plant that belongs to the family Labiatae is widely used in folk medicine as antidiabetic, antibactrial and anti-inflammatory agent. In this study, we evaluated the effect of Teucrium polium on the mouse polymorphonuclear neutrophils. The animals were divided into five groups including four test and one control group, which orally received 50 and 100 mg/kg of aqueou...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2015
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3304